BPM 112 Upstream Processing

This course introduces techniques involved in cell growth and fractionation. Topics include fermentation theory and application, as well as cell harvesting, cell disruption and fractionation methods. Upon completion, students should be able to grow cells, as well as isolate and collect various fractions.

Pre-requisite(s): BPM 111  .
Course is typically offered in Fall
Student Learning Outcomes (SLOs)
Upon completion of the course, students should be able to do the following:

1. Apply fermentation techniques in upstream bioprocessing operations.
2. Culture various cell types under controlled conditions to achieve optimal growth and productivity.
3. Apply appropriate cell harvesting methods to efficiently recover biomass from fermentation or cell culture processes.
4. Demonstrate cell disruption techniques to release intracellular components for downstream processing.
5. Apply fractionation methods to separate and collect desired cellular fractions from disrupted cells.