BPM 113 Downstream Processing

This course introduces a variety of techniques involved in separation procedures. Topics include extraction and precipitation, concentration and molecular filtration methods, as well as different types of chromatography. Upon completion, students should be able to perform separation procedures with an understanding of industrial scale procedures.

Pre-requisite(s): BPM 111  .
Course is typically offered in Fall
Student Learning Outcomes (SLOs)
Upon completion of the course, students should be able to do the following:

1. Apply the principles of extraction and precipitation methods to separate target biomolecules from complex mixtures in downstream bioprocessing.
2. Create concentrated biomolecules without impurities at an industrial scale based on concentration methods.
3. Perform different types of chromatography to purify target proteins, nucleic acids, and other biomolecules.
4. Perform downstream processing workflow that combines extraction, filtration, and chromatography to achieve the desired level of biomolecule purity.
5. Describe scaling up separation techniques from the laboratory to industrial production.